R848, a Toll-like receptor 7/8 agonist, a potential therapy for allergic rhinitis patients
نویسندگان
چکیده
منابع مشابه
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.
BACKGROUND Conjugating immunostimulatory sequences of DNA to specific allergens offers a new approach to allergen immunotherapy that reduces acute allergic responses. METHODS We conducted a randomized, double-blind, placebo-controlled phase 2 trial of a vaccine consisting of Amb a 1, a ragweed-pollen antigen, conjugated to a phosphorothioate oligodeoxyribonucleotide immunostimulatory sequence...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/conf.fimmu.2013.02.00370